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Is this a methanol extract like the extract in this study?

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  • Last Updated:
    Posted on: 14 Nov 2024

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http://*****/article/bbb/65/7/65_1656/_article/-char/en

Acetyl-CoA Carboxylase Inhibitors from Avocado (Persea americana Mill) Fruits
Hironori HASHIMURA1), Chihoko UEDA1), Jun KAWABATA1) and Takanori KASAI1)
1) Laboratory of Food Biochemistry, Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
(Received November 17, 2000)
(Accepted March 19, 2001)
A methanol extract of avocado fruits showed potent inhibitory activity against acetyl-CoA carboxylase, a key enzyme in fatty acid biosynthesis. The active principles were isolated and identified as (5E, 12Z, 15Z)-2-hydroxy-4-oxoheneicosa-5, 12, 15-trienyl (1), (2R, 12Z, 15Z)-2-hydroxy-4-oxoheneicosa-12, 15-dienyl (2), (2R*, 4R*)-2, 4-dihydroxyheptadec-16-enyl (3) and (2R*, 4R*)-2, 4-dihydroxyheptadec-16-ynyl (4) acetates by instrumental analyses.